Table 1 Average MAT titres after vaccination and challenge. Pigs were vaccinated twice (4-week interval) and challenged with different Leptospira serovar (sv) and serogroup (sg) challenge strains, 6 weeks after first vaccination. MAT titres homologous to challenge strain

9

vaccine

sv Canicola

<2

<2

9.6 ± 2.0

9.6 ± 1.3

10

control

sg Canicola

<2

<2

<2

10.3 ± 1.1

10

vaccine

sv Copenhageni

<2

<2

3.8 ± 1.2

9.6 ± 1.0

10

control

sg lcterohaemorrhagiae

<2

<2

<2

10.3 ± 0.7

10

vaccine

sv lcterohaemorrhagiae

<2

<2

<2

91 ± 3.3

10

control

sg lcterohaemorrhagiae

<2

<2

<2

8.7 ± 1.4

10

vaccine

sv Bananal / Liangguan

<2

<2

6.9 ± 1.4

9.3 ± 0.8

9

control

sg Grippotyphosa

<2

<2

<2

91 ± 0.8

8

vaccine

sv Grippotyphosa

<2

<2

4.6 ± 2.4

7.6 ± 1.3

10

control

sg Grippotyphosa

<2

<2

<2

2.0 ± 1.8

10

vaccine

sv Bratislava

<2

6.9 ± 1.2

10.4 ± 0.8

10.5 ± 1.1

9

control

sg Australis

<2

<2

<2

9.9 ± 1.2

9

vaccine

sv Pomona

<2

<2

5.0 ± 4.0

6.7 ± 3.2

10

control

sg Pomona

<2

<2

<2

9.6 ± 0.8

10

vaccine

sv Vughia

<2

<2

<2

8.5 ± 0.8

10

control

sg Tarassovi

<2

<2

<2

9.5 ± 1.0

10

vaccine

sv Tarassovi

<2

<2

2.0 ± 3.2

8.0 ± 1.3

10

control

sg Tarassovi

<2

<2

<2

4.3 ± 1.3