Fig. 1

Clinical course of disease after treatment. Group T1: 8 mg/kg marbofloxacin, one-shot treatment, 11 pigs at Day 0, 10 pigs from Day 0 + 4 h onwards; Group T2: 2.5 mg/kg enrofloxacin, treatment on three consecutive days, 12 pigs; Group T3: 0.9% saline treatment, 11 animals at Day 0, 4 pigs from Day 0 + 4 h onwards, 3 pigs from Day 2 onwards; Day 0 = time of intention to first treatment, h = hours, Day 1 = 24 h after first treatment, Day 2–6 = 48–144 h after first treatment, dotted line = marking the threshold for physiological body temperature of 40.0 °C