Table 4 Least squares mean (±standard error) viral load in serum and nasal/oral swabs, and percentage of RT-qPCR positive pigs (in brackets). Results from RT-qPCR are expressed as log10 RNA copies/mL of serum. A positive result is considered when > 1.7 log10 RNA copies/mL (limit of quantification)
Treatment | Day of study | ||||||
|---|---|---|---|---|---|---|---|
D0 | D67 (Ch) | D70 (Ch + 3) | D73 (Ch + 6) | D75 (Ch + 8) | D77 (Ch + 10) | ||
Viremia | T01 | ≤ 1.7 (0%) | 1.65 ± 0.20 (0%) | 6.60 ± 0.20 (100%) | 6.39 ± 0.20 (100%) | 5.32 ± 0.20 (100%) | 5.29 ± 0.20 (100%) |
T02 | ≤ 1.7 (0%) | 2.25 ± 0.36 (50%) | 2.87 ± 0.36 (50%) | 5.18 ± 0.36 (94%) | 4.18 ± 0.36 (100%) | 2.96 ± 0.36 (69%) | |
T01 vs T02 (p value) | NT | 0.1495 | < 0.0001 | 0.0043 | 0.0071 | < 0.0001 | |
Nasal shedding | T01 | NT | ≤ 1.7 ± 0.19 (0%) | 3.91 ± 0.19 (100%) | 3.98 ± 0.19 (100%) | 2.27 ± 0.19 (61%) | 1.90 ± 0.19 (22%) |
T02 | NT | ≤ 1.7 ± 0.20 (0%) | 1.81 ± 0.20 (12%) | 2.72 ± 0.20 (50%) | 2.35 ± 0.20 (44%) | 1.70 ± 0.20 (0%) | |
T01 vs T02 (p value) | NT | 0.9986 | < 0.0001 | < 0.0001 | 0.7576 | 0.4654 | |
Oral shedding | T01 | NT | 1.70 ± 0.03 (0%) | 3.34 ± 0.21 (83%) | 3.68 ± 0.23 (94%) | 2.57 ± 0.19 (67%) | 2.28 ± 0.20 (39%) |
T02 | NT | 1.75 ± 0.03 (6%) | 2.32 ± 0.22 (56%) | 3.62 ± 0.25 (81%) | 2.30 ± 0.20 (50%) | 1.80 ± 0.22 (12%) | |
T01 vs T02 (p value) | NT | 0.1978 | 0.0009 | 0.8800 | 0.3243 | 0.1096 | |