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Table 4 Least squares mean (±standard error) viral load in serum and nasal/oral swabs, and percentage of RT-qPCR positive pigs (in brackets). Results from RT-qPCR are expressed as log10 RNA copies/mL of serum. A positive result is considered when > 1.7 log10 RNA copies/mL (limit of quantification)

From: Vaccination of 1-day-old pigs with a porcine reproductive and respiratory syndrome virus (PRRSV) modified live attenuated virus vaccine is able to overcome maternal immunity

  Treatment Day of study
D0 D67 (Ch) D70 (Ch + 3) D73 (Ch + 6) D75 (Ch + 8) D77 (Ch + 10)
Viremia T01 ≤ 1.7 (0%) 1.65 ± 0.20 (0%) 6.60 ± 0.20 (100%) 6.39 ± 0.20 (100%) 5.32 ± 0.20 (100%) 5.29 ± 0.20 (100%)
T02 ≤ 1.7 (0%) 2.25 ± 0.36 (50%) 2.87 ± 0.36 (50%) 5.18 ± 0.36 (94%) 4.18 ± 0.36 (100%) 2.96 ± 0.36 (69%)
T01 vs T02 (p value) NT 0.1495 < 0.0001 0.0043 0.0071 < 0.0001
Nasal shedding T01 NT ≤ 1.7 ± 0.19 (0%) 3.91 ± 0.19 (100%) 3.98 ± 0.19 (100%) 2.27 ± 0.19 (61%) 1.90 ± 0.19 (22%)
T02 NT ≤ 1.7 ± 0.20 (0%) 1.81 ± 0.20 (12%) 2.72 ± 0.20 (50%) 2.35 ± 0.20 (44%) 1.70 ± 0.20 (0%)
T01 vs T02 (p value) NT 0.9986 < 0.0001 < 0.0001 0.7576 0.4654
Oral shedding T01 NT 1.70 ± 0.03 (0%) 3.34 ± 0.21 (83%) 3.68 ± 0.23 (94%) 2.57 ± 0.19 (67%) 2.28 ± 0.20 (39%)
T02 NT 1.75 ± 0.03 (6%) 2.32 ± 0.22 (56%) 3.62 ± 0.25 (81%) 2.30 ± 0.20 (50%) 1.80 ± 0.22 (12%)
T01 vs T02 (p value) NT 0.1978 0.0009 0.8800 0.3243 0.1096
  1. NT: not tested
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Porcine Health Management

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