Table 3 Cytokine measure geometric mean (±SD) results
Treatment | Day of study | ||||||
|---|---|---|---|---|---|---|---|
3 | 7 | 28 | 83 | 125 (DC-1) | 132 (DC + 6) | ||
IL-10 | T01 | ND | ND | 4.8 ± 1.0 (1/5) | |||
T02 | ND | ND | 5.2 ± 1.7 (1/8) | ||||
T03 | ND | ND | 10.1 ± 6.4 (2/8) | ||||
P value | T01 vs T02 | NS | |||||
T01 vs T03 | NS | ||||||
T02 vs T03 | NS | ||||||
IL-8 | T01 | ND | ND | 48.1 ± 22.9 (3/5) | |||
T02 | ND | ND | 33.8 ± 12.7 (3/8) | ||||
T03 | ND | ND | 69.6 ± 26.2 (6/8) | ||||
P value | T01 vs T02 | NS | |||||
T01 vs T03 | NS | ||||||
T02 vs T03 | NS | ||||||
IFN-α | T01 | ND | 1.9 ± 0.0 (1/5) | ||||
T02 | 9.8 ± 6.1 (10/10) | 32.8 ± 11.8 (10/10) | |||||
T03 | 9.5 ± 9.7 (9/10) | 14.1 ± 9.9 (10/10) | |||||
TNF-α | T01 | ND | ND (1/5)a | ND | 62.7 ± 7.6 (1/5) | ND | 29.1 ± 1.5 |
T02 | ND | ND | ND | ND (1/8)a | ND | 41.9 ± 1.6 (1/8) | |
T03 | ND | ND | ND | ND (2/8)a | ND | 78.2 ± 2.9 (1/8) | |
P value | T01 vs T02 | NS | |||||
T01 vs T03 | NS | ||||||
T02 vs T03 | NS | ||||||
IFN-γ | T01 | 1.6 ± 0.0 (5/5) | 1.6 ± 0.0 (4/5) | 0.0 ± 0.0 (3/4) | 8.1 ± 0.5 (3/4) | ||
T02 | 22.1 ± 1.1 (9/10) | 80.5 ± 8.2 (8/8) | 166.5 ± 7.1 (8/8) | 133.5 ± 5.7 (8/8) | |||
T03 | 51.3 ± 4.1 (8/9) | 77.2 ± 8.2 (8/8) | 102.2 ± 4.3 (8/8) | 155.7 ± 6.6 (8/8) | |||
P value | T01 vs T02 | 0.0003 | 0.0033 | ||||
T01 vs T03 | 0.0108 | 0.0011 | |||||
T02 vs T03 | NS | NS | |||||