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Table 1 Recombinant LAVs tested in vivo, specially indicating those providing protection again the Genotype II virus currently circulating in Asia and Europe (bolded data)

From: African swine fever vaccines: a promising work still in progress

Deleted gene(s) Protein(s) Parental ASFV Recombinant LAVs Target cells Reference
Strain Virulence Virulence Protection
EP402R CD2v BA71V Non-pathogenic Non-pathogenic None Vero [45]
Malawi Lil-20/1 Virulent Virulent None Macrophages [46]
Georgia2010 Virulent Virulent None Macrophages [47]
BA71 Virulent Attenuated BA71, E75, Georgia2007/1 COS-1 & Macrophages [48]
DP71L NL Malawi Lil-20/1 Vrulent Virulent Malawi Macrophages [49, 50]
E70 Virulent Attenuated E70 Macrophages [50, 51]
B119L 9GL Pretoriuskop/96/4 Virulent Attenuated Pretoriuskop/96/4 Macrophages [52]
Malawi Lil-20/1 Virulent Attenuated Malawi Macrophages [53]
Georgia2010 Virulent Attenuated Georgia2010 Macrophages [54]
DP96R UK E70 Virulent Attenuated E70 Macrophages [55]
DP148R   Benin Virulent Attenuated Benin Macrophages [56]
MGF360 & MGF505   Benin Virulent Attenuated Benin Macrophages [57]
Georgia2010 Virulent Attenuated Georgia2010 Macrophages [58]
B119L & DP96R 9GL & UK Georgia2010 Virulent Attenuated Georgia2010 Macrophages [59]
MGF360 & MGF505 & B119L   Georgia2010 Virulent Highly attenuated None Macrophages [60]
B119L & DP96R & DP71L 9GL & UK & NL Georgia2010 Virulent Highly attenuated None Macrophages [61]
DP71L & DP96R NL & UK OUR T88/3 Attenuated Highly attenuated None Macrophages [62]
A238L
A224L
EP153R
NFAT regulator
Apoptosis inhibitor
MHC-I antigen presenting modulator
NH/P68 Attenuated Highly attenuated L60 COS-7 & Macrophages [63]
MGF360 & MGF505 & EP402R MGF505-1R, MGF505-2R, MGF505-3R, MGF360-12 L, MGF360-13 L, MGF360-14 L & CD2v China HLJ/18 Virulent Attenuated China HLJ/18 Macrophages [64]