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Table 2 ASFV serological immunodeterminants, indicating those described to be recognized by sera from pigs recovered from ASFV infection (antigenic) or to induce immune responses after in vivo immunization (immunogenic)

From: African swine fever vaccines: a promising work still in progress

Gene name Protein Antigenic Reference Immunogenic Reference
Structural
 A104R Histone-like DNA-binding protein Yes [69, 70] Yes [71]
 A137R P11.5 Yes [72]
 B438L p49 Yes/Low [73, 74]
 B602L p72 chaperone Yes [69, 70] Yes [74, 75]
 B646L p72, major capsid protein Yes [27, 69, 76] Yes [71, 72, 77, 78]
 CP204L p30 Yes [27, 69] Yes [38, 71,72,73, 77,78,79]
 CP2475L pp220 Yes [72]
 CP2475L/partial p37 Yes [71]
 CP530R pp62 Yes [80] Yes [38, 81]
 CP530R/partial p35 Yes [37, 78]
 CP530R/partial p15 Yes [37, 78]
 D117L Major transmembrane
protein p17
Yes [73]
 E183L p54 Yes [27, 69, 70] Yes/Low [37, 71, 73, 77,78,79]
 EP153R C-type lectin Yes [73]
 EP402R HA/CD2v Yes [82] Yes [71, 73, 78]
 K78R p10, DNA-binding Yes [69]
 KP177R p22 Yes/Low [73, 77]
 E120R p14.5 Low [73]
 H108R Inner envelope Low [73]
 O61R p12 Yes [73]
Non-structural
 B119L 9GL, virus assembly Yes [74]
 F334L RNA reductase Yes [69]
 I215L Ubiquitin conjugating enzyme Yes [38]
 K196R Thymidine kinase Yes [69]
 L10L KP177R-related Yes [73]
 NP419L DNA ligase Yes [69]
Uncharacterized
 A151R Yes [74]
 C129R Yes [38]
 C44L Yes [69]
 CP312R Yes [69] Yes [78]
 E184L Yes [69]
 K145R Yes [69]
 K205R Yes [69, 70, 75] Yes [74]
 M448R Yes [38]
Multigene families
 MGF110-4 L XP124L Yes [38]
 MGF110-5 L V82L Yes [38]