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Table 3 ASFV-specific T-cell determinants, indicating those described to be recognized by PBMCs from pigs recovered from ASFV infection (antigenic) and those inducing T-cell responses after in vivo immunization (immunogenic)

From: African swine fever vaccines: a promising work still in progress

Gene name Protein Antigenic Reference Immunogenic Reference
Structural
 B602L p72 chaperone Yes [73]
 B646L p72 Yes [38, 86] Yes [38, 71, 73]
 CP204L p30 Yes [38, 87] Yes [38, 71, 73]
 CP2475L pp220 Yes [73]
 CP530R pp62 Yes [38] Yes [38, 71, 73]
 CP530R/partial p15 Yes [37]
 D117L Low [73]
 E183L p54 Yes [71, 73]
 E248R Transmembrane myristoylated protein Yes [38]
 EP153R C-type lectin Yes [88] Yes [73]
 EP402R HA/CD2v Yes [88] Yes [73, 89]
 H108R Inner envelope Low [73]
 I239L Yes [90]
 K78R p10 Yes [38] No [38]
 KP177R p22 Yes [38] Yes [73]
 B438L p49 Yes [73, 74]
 E199L j18L Yes [73]
 O61R p12 Yes [73]
Non-structural
 A179L Low [73]
 B119L 9GL, virus assembly Yes [74]
 C475L Poly(A) polymerase Yes [38]
 C962R DNA primase Yes [38]
 DP71L Protein phosphatase 1 regulator Low [73]
 E165R dUTPase Yes [38] Yes [38]
 E296R AP endonuclease Yes [38]
 F1055L Helicase Yes [73]
 F334L RNA reductase Yes [38]
 G1211R DNA polymerase Yes [73]
 G1340L VACV A7 early transcription factor large subunit-like Yes [86] Low [73]
 H339R Alpha-NAC binding protein Yes [38]
 H359L RNA polymerase subunit 3–11 Yes [38]
 I215L Ubiquitin conjugating enzyme Yes [38] Yes [38]
 I329L TLR inhibitor Low [73]
 NP1450L RNA polymerase subunit 1 Yes [73]
 NP419L DNA ligase Yes [38] Yes [73]
 NP868R mRNA-capping enzyme Yes [38]
 O174L DNA polymerase X Yes [38]
Multigene families
 MGF110-1 L Yes [38] Yes [38]
 MGF110-2 L Low [73]
 MGF110-4 L XP124L Yes [38] Yes [38]
 MGF110-5 L V82L Yes [38] Yes [38]
 MGF300-1 L J268L Yes [38] Low [73]
 MGF300-2R Low [73]
 MGF360-11 L KP362L Yes [73]
 MGF360-15R Low [73]
 MGF360-16R Yes [38]
 MGF360-18R Low [73]
 MGF360-1 L KP360L Yes [73]
 MGF505-11 L Yes [38]
 MGF505-4R Yes [73]
 MGF505-5R A498R    Yes [73]
Uncharacterized
 285 L Yes [38]
 A151R Yes [38] Yes [38]
 B407L Low [73]
 C129R Yes [38] Yes [38]
 C257L Yes [38]   
 CP312R Yes [38] Yes [38]
 CP312R Yes [31, 91]
 D339L Low [73]
 DP238L Yes [38]
 E120R . Low [73]
 E146L Yes [38] Yes [38]
 E184L Yes [38] Yes [38]
 EP364R Yes [73]
 F317L Yes [73]
 I243L Yes [38]
 I73R Yes [38] No [38]
 K205R Yes [38] Yes [73, 74]
 L8L Yes [38]
 L10L Yes [38] Low [38, 73]
 M1249L Yes [38] Low [73]
 M448R Yes [38] Yes [38]
 Complement (183875–184,183) Low [73]