Biosafety steps in the manufacturing process of spray-dried plasma: a review with emphasis on the use of ultraviolet irradiation as a redundant biosafety procedure

Table 1 Reduction factors obtained for different viruses subjected to the spray-drying treatment

Virus	Nucleic acid	Envelope	Virus size (nm)	Virus inactivation expressed as Log 10 TCID₅₀	Reference
PRRSV	ssRNA	Yes	50–65	4.0 log	[31]
PEDV	ssRNA	Yes	90–190	> 5.2 log	[34]
PEDV	ssRNA	Yes	90–190	> 3.6 log	[33]
PRV	ssDNA	Yes	150–180	5.3 log	[31]
ASFV	dsDNA	Yes	80–200	~ 4.0 log	[35]
SVDV	ssRNA	No	22–30	6.0 log	[32]

ISSN: 2055-5660