Evaluation of classical swine fever E2 (CSF-E2) subunit vaccine efficacy in the prevention of virus transmission and impact of maternal derived antibody interference in field farm applications

Table 2 Histopathological score of groups A, B, and C

		Groups	A				B				C
Organs	Criteria^a	Pigs	A1	A2	A3	A4	B1	B2	B3	B4	C5	C6
Central nervous system	Cuffing		1	0	1	0	0	0	0	0	3	3
	Endothelium hypertrophy/ hyperplasia		1	1	1	1	1	1	1	1	3	3
	Gliosis		1	1	1	0	0	0	0	1	3	3
Spleen	Lymphoid necrosis		0	0	0	0	0	0	0	0	0	0
Spleen	Lymphoid depletion		0	0	1	0	0	1	0	1	2	2
Tonsil	Lymphoid necrosis		1	1	1	1	1	1	1	1	3	1
Tonsil	Lymphoid depletion		0	0	0	0	0	0	0	0	0	1
Lymph nodes	Lymphoid depletion		1	1	1	1	0	0	0	0	2	2
Lymph nodes	Lymphoid necrosis		0	0	0	0	0	0	0	0	1	0
Kidney	Interstitial nephritis		0	0	0	1	0	0	0	0	2	0
	Total score		5	4	6	4	2	3	2	4	19	15

^aThe histopathological score system used in the study was described by Malswamkima et al., in previous study (0–3 scale: normal-0, mild-1, moderate-2, severe-3). The tissues including central nervous system, spleen, tonsil, lymph nodes and kidney were blind scored by three trained pathologists

ISSN: 2055-5660