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Table 3 Effects of guanidinoacetic acid (GAA) on plasma free amino acid profile in finishing pigs (nmol/mL)

From: Guanidine acetic acid supplementation altered plasma and tissue free amino acid profiles in finishing pigs

Items GAA, mg/kg SEM P-value
0 500 1000 1500 ANOVA Linear Quadratic
EAA
Methionine 35.50 39.00 34.83 31.60 3.13 0.476 0.310 0.300
Threonine 128.33 141.00 138.67 114.60 9.56 0.286 0.413 0.083
Valine 224.67 243.33 236.83 191.00 15.24 0.132 0.179 0.051
Isoleucine 77.83 87.33 87.50 71.60 5.29 0.170 0.567 0.035
Leucine 195.67ab 205.67a 184.50ab 164.60b 8.25 0.017 0.008 0.081
Phenylalanine 75.00 78.17 73.17 67.20 3.46 0.202 0.096 0.196
Tryptophan 62.17 52.83 61.67 39.60 6.91 0.137 0.100 0.398
Lysine 192.17 183.83 193.67 146.60 12.86 0.130 0.086 0.205
Histidine 89.00 83.17 88.33 78.60 3.68 0.293 0.202 0.663
Arginine 147.33 136.83 142.50 129.20 7.49 0.515 0.240 0.888
NEAA
Serine 122.33 118.83 108.83 99.80 7.57 0.228 0.046 0.728
Glycine 914.33a 863.00ab 845.33ab 727.00b 35.63 0.014 0.002 0.367
Alanine 354.00 342.83 341.00 361.40 17.96 0.843 0.807 0.394
Glutamate 74.83 84.83 80.83 74.60 7.38 0.748 0.939 0.307
Glutamine 233.00 256.17 261.83 252.60 17.11 0.689 0.415 0.384
Aspartic acid 17.40 15.50 21.67 15.80 2.48 0.393 0.850 0.498
Asparagine 30.50 35.75 44.83 31.40 4.81 0.270 0.554 0.104
Tyrosine 84.50 83.17 92.50 86.80 4.98 0.596 0.506 0.700
Proline 239.67 215.33 226.33 211.00 12.34 0.392 0.203 0.704
Non-protein amino acids and derivatives/ metabolites of amino acids
Ornithine 59.17ab 67.00a 61.17ab 50.40b 3.57 0.033 0.079 0.016
Taurine 86.17 97.00 103.67 81.80 5.89 0.120 0.971 0.025
Citrulline 74.00 74.17 74.17 69.00 5.03 0.884 0.561 0.620
Hydroxyproline 101.00 127.00 133.67 126.00 16.34 0.570 0.296 0.352
Cystathionine 5.50 9.00 8.20 7.25 0.92 0.130 0.174 0.067
α-aminoadipic acid 39.67 37.67 43.00 39.00 2.94 0.822 0.864 0.829
1-Methyl-L-histidine 12.40 15.00 15.80 11.00 1.84 0.309 0.704 0.078
Urea 4261.33 4247.67 4330.50 3845.40 432.94 0.869 0.589 0.597
∑EAA 1165.50 1198.33 1180.00 995.00 47.30 0.061 0.053 0.054
∑NEAA 2053.17 1988.00 2001.50 1844.60 61.50 0.165 0.051 0.483
TAA 3671.17ab 3674.5ab 3695.67a 3273.2b 103.51 0.036 0.032 0.058
  1. SEM standard error of the mean, EAA essential amino acids, NEAA nonessential amino acids, TAA total amino acids
  2. Dietary treatments were: basal diet + 0, 500, 1000, and 1500 mg/kg GAA, respectively. n = 6
  3. a, bMean within rows with different letters differ significantly (P < 0.05)
  4. Bold indicates P < 0.05