Table 3 The top 5 upregulated gene transcription fold changes relative to the positive control for each treatment in response to LPS challenge or no challenge for the Negative control were compiled

1

15

0

5

6

0.166

CIB3

Integrin

1

13

5

4

4

1

CASS4

Cellular adhesion

1

11

12

3

18

0.2

TLL2

Degradation of the extracellular matrix and Collagen formation

1

2.666

2.666

15.66

18

0.375

SGCA

Muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix

1

0.818

1.272

0.272

0.909

11

ARMC12

Mitochondrial peripheral membrane protein and functions as an adherence factor between mitochondria in cultured cells

1

8

2

13

7

0.071

IGFBP4

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture

1

6

12.25

7.5

11.75

0.5

NR4A3

Regulation of proliferation, survival and differentiation of many different cell types and also in metabolism and inflammation

1

0.375

0.25

24

10.375

1.6

INHBA

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins

1

17

13

24

25

0.090

CLSTN3

Calcium-mediated postsynaptic signals

1

11

1

0

1

0.076

SLC45A2

Membrane-associated transporter protein

1

10

22

12

7

0.166

CNKSR2

Mediate the mitogen-activated protein kinase pathways

1

5

11

5

10

0.166

GPR68

G protein-coupled receptor 1, OGR1 responds to extracellular acidity and regulates a variety of cellular functions

1

8

1

0

12

0

IZUMO1R

Gamets adhesion

1

0.333

0.266

0.333

0.333

15

MYOZ2

Function in slow-twitch skeletal muscle, which functions to tether calcineurin to alpha-actinin at Z-discs

1

0.25

0.375

0.0625

0.125

16

TNNT2

Instructions for making a protein called cardiac troponin T

1

0.090

0.136

0.272

0

22

SFTPC

Production of surfactant protein-C