A novel octavalent combined Erysipelas, Parvo and Leptospira vaccine provides (cross) protection against infection following challenge of pigs with 9 different Leptospira interrogans serovars

Table 2 Reisolation of Leptospira from blood. Pigs were vaccinated twice (4-week interval) and challenged with different Leptospira serovar (sv) and serogroup (sg) challenge strains, 6 weeks after first vaccination. A pig was considered infected if at least once a positive blood isolation was found. n.a. = not applicable

									# pigs infected	# blood isolations
n	group	challenge with	1	2	3	4	7	10
9	vaccine	sv Canicola	0	0	0	0	0	0	0**	n.a.
10	control	sg Canicola	10	10	10	10	1	0	10	n.a.
10	vaccine	sv Copenhageni	0	0	0	0	0	0	0**	n.a.
10	control	sg Icterohaemorrhagiae	10	10	8	4	1	0	10	n.a.
10	vaccine	sv Icterohaemorrhagiae	2	0	0	0	0	0	2**	2**
10	control	sg Icterohaemorrhagiae	9	6	2	0	0	0	9	17
10	vaccine	sv Bananal / Liangguan	0	0	0	0	0	0	0**	n.a.
9	control	sg Grippotyphosa	6	8	6	2	0	0	8	n.a.
8	vaccine	sv Grippotyphosa	0	0	0	0	0	0	0**	n.a.
10	control	sg Grippotyphosa	6	1	0	0	0	0	6	n.a.
10	vaccine	sv Bratislava	0	0	0	0	0	0	0**	n.a.
9	control	sg Austrais	6	4	0	0	0	0	6	n.a.
9	vaccine	sv Pomona	0	0	0	0	0	0	0**	n.a.
10	control	sg Pomona	10	10	10	9	2	0	10	n.a.
10	vaccine	sv Vughia	0	0	0	0	0	0	0**	n.a.
10	control	sg Tarassovi	10	9	1	1	0	0	10	n.a.
10	vaccine	sv Tarassovi	2	0	0	0	0	0	2	2*
10	control	sg Tarassovi	6	2	1	1	0	0	6	10

ISSN: 2055-5660