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Table 3 PRRSV-viral RNA load in serum

From: Long duration of immunity against a type 1 heterologous PRRS virus challenge in pigs immunised with a novel PRRS MLV vaccine: a randomised controlled study

  

PRSSV-viral RNA load in serum (log10 GE/mL)

Study

DPC

Group

n

Mean

95% CI

Median (IQR)

p-value*

20-week

0

1

22

0.00

0.00–0.00

0.00 (0.00)

1.0000

2

20

0.00

0.00–0.00

0.00 (0.00)

3

1

22

3.84

3.00–4.29

3.79 (1.29)

<  0.0001

2

20

5.30

5.06–5.52

5.34 (0.54)

7

1

22

0.14

0.00–0.00

0.00 (0.00)

<  0.0001

2

20

4.00

3.44–4.59

3.95 (1.26)

10

1

22

0.27

0.00–0.00

0.00 (0.00)

<  0.0001

2

20

3.23

3.00–3.37

3.00 (0.51)

24-week

0

1

20

0.00

0.00–0.00

0.00 (0.00)

1.0000

2

19

0.00

0.00–0.00

0.00 (0.00)

3

1

20

3.39

3.00–4.04

3.78 (1.13)

<  0.0001

2

19

5.06

4.85–5.36

5.13 (0.56)

7

1

19

0.32

0.00–0.00

0.00 (0.00)

<  0.0001

2

19

3.85

3.00–4.53

3.87 (1.53)

10

1

20

0.00

0.00–0.00

0.00 (0.00)

<  0.0001

2

19

2.75

3.00–3.37

3.00 (0.37)

26-week

0

1

21

0.00

0.00–0.00

0.00 (0.00)

1.0000

2

20

0.00

0.00–0.00

0.00 (0.00)

3

1

21

4.42

3.93–5.28

4.44 (1.51)

<  0.0001

2

20

5.81

5.75–6.00

5.88 (0.32)

7

1

21

0.61

0.00–0.00

0.00 (0.00)

<  0.0001

2

20

5.30

4.86–5.69

5.30 (1.08)

10

1

21

0.00

0.00–0.00

0.00 (0.00)

<  0.0001

2

20

3.97

3.71–4.42

4.24 (1.18)

  1. CI distribution free confidence interval of the median, DPC day post-challenge, GE genome equivalent, IQR interquartile range, MLV modified live virus, n number of pigs included in analysis, PRRS porcine reproductive and respiratory syndrome, PRRSV PRRS virus
  2. Group 1 = PRRS 94881 MLV vaccinated; Group 2 = challenge controls
  3. *p-values were calculated using the Wilcoxon-Mann-Whitney test