Porcine Health Management

Table 4 PRRSV-viral RNA cumulative loads in serum

From: Long duration of immunity against a type 1 heterologous PRRS virus challenge in pigs immunised with a novel PRRS MLV vaccine: a randomised controlled study

			AUC values (log₁₀ GE/mL)
Study	DPC	Group	n	Mean	95% CI	Median (IQR)	p-value^*
20-week	0–10	1	22	14.33	10.50–17.80	13.32 (7.3)	< 0.0001
	0–10	2	20	37.40	35.02–39.37	37.44 (4.54)	< 0.0001
	3–10	1	22	8.57	6.00–10.46	7.61 (4.46)	< 0.0001
	3–10	2	20	29.44	27.71–31.08	29.74 (3.76)	< 0.0001
24-week	0–10	1	19	12.87	10.50–15.16	13.23 (4.66)	< 0.0001
	0–10	2	19	35.31	32.78–38.22	36.07 (5.68)	< 0.0001
	3–10	1	19	7.83	6.00–8.86	7.56 (2.86)	< 0.0001
	3–10	2	19	27.72	25.16–30.72	28.29 (5.70)	< 0.0001
26-week	0–10	1	21	17.61	13.76–19.53	15.54 (5.95)	< 0.0001
	0–10	2	20	44.84	43.23–48.03	44.77 (6.24)	< 0.0001
	3–10	1	21	10.97	7.86–11.16	8.88 (3.40)	< 0.0001
	3–10	2	20	36.12	34.60–38.53	36.43 (5.23)	< 0.0001

AUC area under the concentration-time curve, CI distribution free confidence interval of the median, DPC day post-challenge, GE genome equivalent, IQR interquartile range, MLV modified live virus, n number of pigs included in analysis, PRRS porcine reproductive and respiratory syndrome, PRRSV PRRS virus
Group 1 = PRRS 94881 MLV vaccinated; Group 2 = challenge controls
^*p-values were calculated using the Wilcoxon-Mann-Whitney test

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ISSN: 2055-5660

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