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Table 1 Experimental design

From: Safety and long-lasting immunity of the combined administration of a modified-live virus vaccine against porcine reproductive and respiratory syndrome virus 1 and an inactivated vaccine against porcine parvovirus and Erysipelothrix rhusiopathiae in breeding pigs

 

Day of the experiment

 

0

0 (+ 4 h)

1

21

21 (+ 4 h)

22

28

42

147

147 (+ 4 h)

148

154

Treatmenta

X

  

X

    

X

   

Systemic reactionsb

X

X

X

X

X

X

  

X

X

X

 

Local reactionsc

X

X

X

X

X

X

 

X

X

X

X

 

Body temperature

X

X

X

X

X

X

 

X

X

X

X

 

Oral Fluid collection

X

  

X

   

X

X

  

X

Blood Sampling

X

  

X

  

X

X

X

  

X

  1. aGroup V (n = 6) was intramuscularly vaccinated with the combined administration of a PRRSV MLV vaccine and an inactivated PPV and Erysipelothrix rhusiopathiae vaccine. Group C (n = 4) was maintained as a control and received PBS
  2. bSystemic reactions: (0) active animal that responded to stimuli; (1) poorly active but responded to weak stimuli; (2) did not respond to weak stimuli, but to strong ones; (3) animal did not respond to strong stimuli, such as forcing them to get up or walk
  3. cThe inoculation site could be distinguished (Y/N); Pain at the injection site (Y/N); Inflammation: (0) no inflammatory reaction, (1) slight, from 0 to 3 cm, (2) moderate, from 3 to 5 cm; and (3) severe, more than 5 cm; Presence of a nodule (Y/N and size in cm)