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Fig. 3 | Porcine Health Management

Fig. 3

From: Evaluation of classical swine fever E2 (CSF-E2) subunit vaccine efficacy in the prevention of virus transmission and impact of maternal derived antibody interference in field farm applications

Fig. 3

Evaluation of vaccine induced immune response on sows and the passive immunity of piglets. Sows were immunized with two doses of CSF-E2 vaccine at 3 and 5 weeks before parturition (group D, n = 25) or one dose of LPC vaccine before insemination (group E, n = 35). a The CSF-specific antibody level was detected using an IDEXX CSFV Ab test kit to monitor vaccine induced immune response. The gray dotted line indicates a positive antibody response (blocking percentage > 40%). b The saliva CSFV RNA was assessed for 1 month after vaccination using real-time PCR. Pearson’s chi-square test with Yate’s continuity correction showed a significant difference between the CSFV positive count of groups D and E (p < 0.001). c The piglet serum samples randomly selected from CSF-E2 vaccinated sows (group F, n = 20) and LPC vaccinated sows (group G, n = 20) were analyzed by using the IDEXX CSFV Ab test kit. The mean blocking percentage of each group was calculated and Welch’s two-sample t-test was performed to evaluate the statistical difference between groups. *** p < 0.001

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