Fig. 1
Heatmaps for Pearson r correlation1 between serotonin receptors2, performance traits3, jejunum morphometry4 and immune biomarkers5 in 1- and 15-day post-weaning piglets. 1Pearson r correlation1 with P values < 0.05 are outlined in red and P values < 0.10 are outlined in blue. 2mRNA expression (log 2) of serotonin (5-HT) receptors (5-HTR3, 5-HTR4, and 5-HTR7) for jejunum (J) and colon (C). 3Body weight (BW) at weaning (BW0), at 15 days post-weaning (BW15) and average daily gain between weaning and 15 days post-weaning (ADG015). 4Villi height, crypt depth and ratio villi height to crypt depth for jejunum. 5Immune parameters = mRNA expression (log 2) of 11 cytokines: interleukin (IL)-1α (IL1a), IL-1β (IL1b), IL-6 (IL6), IL-8 (IL8), IL-10 (IL10), IL-12p35 (IL12a), IL-12p40 (IL12b), tumor necrosis factor alpha (TNFa), interferon alpha and gamma (IFNa and IFNg), transforming growth factor betta (TGFb) for jejunum, colon and PBMCs; and IgA-producing cells (IgAcell) for jejunum (J) and colon (C); and lymphocytes B phenotype CD21+ (B), natural killer cells phenotype CD3−16+56+ (NK) and lymphocytes T phenotypes CD3+ (CD3), T helper CD3+CD4+ (Th), T cytotoxic CD3+CD8+ (Tc), CD4+CD8+ (CD4CD8), and CD4−CD8− (CD4CD8neg) from blood