Fig. 3

Partial least square regression (PLS) and two extracted factors for A dataset-C and B subset of 15 days post-weaning of dataset-C. A Variance of serotonin (5-HT) receptors (5-HTR3, 5-HTR4, and 5-HTR7) explained by time (1- and 15-days post-weaning), tissue (jejunum and colon), mRNA expression of 12 immune biomarkers¹ from jejunum and colon, and body weight at weaning (BW0) from piglets at 1 day (n = 9) and 15 days post-weaning (n = 10). B Variance of average daily gain from weaning to 15 days post-weaning (ADG015) explained by BW0, tissue (jejunum and colon), and mRNA expression of 12 immune biomarkers¹ and serotonin receptors² from piglets at 15 days post-weaning (n = 10). ¹mRNA expression (log 2) of 11 cytokines: interleukin IL-1α (IL1a), IL-1β (IL1b), IL-6 (IL6), IL-8 (IL8), IL-10 (IL10), IL-12p35 (IL12a), IL-12p40 (IL12b), tumor necrosis factor alpha (TNFa), interferon alpha and gamma (IFNa and IFNg), transforming growth factor betta (TGFb) for jejunum, colon and PBMCs; and IgA-producing cells (IgAcell) for jejunum and colon. ²mRNA expression (log 2) of serotonin (5-HT) receptors (HTR3, HTR4, and HTR7)