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Table 7 Effects of guanidinoacetic acid (GAA) on pancreatic free amino acid profile in finishing pigs (mg/kg dry pancreas)

From: Guanidine acetic acid supplementation altered plasma and tissue free amino acid profiles in finishing pigs

Items GAA, mg/kg SEM P-value
0 500 1000 1500 ANOVA Linear Quadratic
EAA
Methionine 0.40 0.35 0.45 0.27 0.09 0.538 0.464 0.429
Threonine 2.86 1.77 2.08 1.56 0.33 0.113 0.047 0.456
Valine 3.83 2.63 3.05 2.12 0.44 0.136 0.049 0.792
Isoleucine 1.52 1.15 1.43 0.85 0.20 0.161 0.090 0.629
Leucine 9.45 7.20 8.46 5.87 1.21 0.259 0.116 0.894
Phenylalanine 5.33 4.10 4.97 3.21 0.63 0.125 0.072 0.685
Tryptophan 1.68a 1.77a 2.15a 0.62b 0.33 0.042 0.128 0.024
Lysine 5.37 4.09 5.04 3.24 0.75 0.251 0.140 0.743
Histidine 1.27 0.94 1.32 1.27 0.20 0.900 0.854 0.737
Arginine 3.58 2.86 3.47 2.50 0.66 0.644 0.399 0.859
NEAA
Serine 5.29 4.31 4.97 4.09 0.63 0.534 0.321 0.938
Glycine 10.27 9.64 10.96 8.67 1.09 0.515 0.486 0.457
Alanine 12.02 11.36 11.10 11.93 1.19 0.937 0.924 0.543
Glutamate 18.67 19.58 20.25 17.45 2.12 0.865 0.790 0.459
Glutamine 0.35 0.27 0.47 0.47 0.11 0.442 0.237 0.663
Aspartic acid 5.31 4.41 4.52 3.62 0.66 0.405 0.121 0.996
Asparagine 2.52 1.37 1.66 1.30 0.31 0.114 0.057 0.310
Cystine 0.37 0.34 0.43 0.29 0.04 0.423 0.658 0.273
Tyrosine 4.76 4.00 4.51 3.47 1.02 0.825 0.480 0.891
Proline 4.00a 3.42ab 3.13ab 2.48b 0.33 0.036 0.005 0.930
Non-protein amino acids and derivatives/metabolites of amino acids
Ornithine 1.37 1.31 1.38 1.17 0.15 0.830 0.537 0.654
Taurine 6.57 6.31 6.28 6.70 0.70 0.974 0.914 0.658
Hydroxyproline 1.18 1.32 1.29 0.89 0.11 0.051 0.067 0.032
Cystathionine 3.72 2.61 3.16 2.22 0.45 0.173 0.082 0.860
a-aminoadipic acid 1.32 1.21 1.38 1.47 0.22 0.870 0.549 0.658
a-amino-n-butyric acid 0.39 0.27 0.39 0.28 0.08 0.556 0.573 0.782
Phosphoethanolamine 16.54 16.99 15.47 17.21 2.02 0.936 0.957 0.761
Ethanolamine 0.50b 0.43b 0.37b 2.28a 2.02 0.001 0.001 0.002
Urea 0.42b 0.39b 0.59ab 1.07a 0.21 0.015 0.004 0.123
∑EAA 33.60 25.14 31.32 20.87 4.46 0.247 0.148 0.836
∑NEAA 77.45 71.58 75.84 66.40 7.10 0.711 0.384 0.808
TAA 111.04 96.72 107.16 87.27 11.15 0.473 0.250 0.811
  1. SEM standard error of the mean, EAA essential amino acids, NEAA nonessential amino acids, TAA total amino acids
  2. Dietary treatments were: basal diet + 0, 500, 1000, and 1500 mg/kg GAA, respectively. n = 6
  3. a, bMean within rows with different letters differ significantly (P < 0.05)
  4. Bold indicates P < 0.05