Guanidine acetic acid supplementation altered plasma and tissue free amino acid profiles in finishing pigs

Cui, Yiyan; Tian, Zhimei; Yu, Miao; Deng, Dun; Lu, Huijie; Song, Min; Ma, Xianyong; Wang, Limin

doi:10.1186/s40813-022-00269-8

Porcine Health Management

Table 7 Effects of guanidinoacetic acid (GAA) on pancreatic free amino acid profile in finishing pigs (mg/kg dry pancreas)

From: Guanidine acetic acid supplementation altered plasma and tissue free amino acid profiles in finishing pigs

Items	GAA, mg/kg				SEM	P-value
Items	0	500	1000	1500	SEM	ANOVA	Linear	Quadratic
EAA
Methionine	0.40	0.35	0.45	0.27	0.09	0.538	0.464	0.429
Threonine	2.86	1.77	2.08	1.56	0.33	0.113	0.047	0.456
Valine	3.83	2.63	3.05	2.12	0.44	0.136	0.049	0.792
Isoleucine	1.52	1.15	1.43	0.85	0.20	0.161	0.090	0.629
Leucine	9.45	7.20	8.46	5.87	1.21	0.259	0.116	0.894
Phenylalanine	5.33	4.10	4.97	3.21	0.63	0.125	0.072	0.685
Tryptophan	1.68^a	1.77^a	2.15^a	0.62^b	0.33	0.042	0.128	0.024
Lysine	5.37	4.09	5.04	3.24	0.75	0.251	0.140	0.743
Histidine	1.27	0.94	1.32	1.27	0.20	0.900	0.854	0.737
Arginine	3.58	2.86	3.47	2.50	0.66	0.644	0.399	0.859
NEAA
Serine	5.29	4.31	4.97	4.09	0.63	0.534	0.321	0.938
Glycine	10.27	9.64	10.96	8.67	1.09	0.515	0.486	0.457
Alanine	12.02	11.36	11.10	11.93	1.19	0.937	0.924	0.543
Glutamate	18.67	19.58	20.25	17.45	2.12	0.865	0.790	0.459
Glutamine	0.35	0.27	0.47	0.47	0.11	0.442	0.237	0.663
Aspartic acid	5.31	4.41	4.52	3.62	0.66	0.405	0.121	0.996
Asparagine	2.52	1.37	1.66	1.30	0.31	0.114	0.057	0.310
Cystine	0.37	0.34	0.43	0.29	0.04	0.423	0.658	0.273
Tyrosine	4.76	4.00	4.51	3.47	1.02	0.825	0.480	0.891
Proline	4.00^a	3.42^ab	3.13^ab	2.48^b	0.33	0.036	0.005	0.930
Non-protein amino acids and derivatives/metabolites of amino acids
Ornithine	1.37	1.31	1.38	1.17	0.15	0.830	0.537	0.654
Taurine	6.57	6.31	6.28	6.70	0.70	0.974	0.914	0.658
Hydroxyproline	1.18	1.32	1.29	0.89	0.11	0.051	0.067	0.032
Cystathionine	3.72	2.61	3.16	2.22	0.45	0.173	0.082	0.860
a-aminoadipic acid	1.32	1.21	1.38	1.47	0.22	0.870	0.549	0.658
a-amino-n-butyric acid	0.39	0.27	0.39	0.28	0.08	0.556	0.573	0.782
Phosphoethanolamine	16.54	16.99	15.47	17.21	2.02	0.936	0.957	0.761
Ethanolamine	0.50^b	0.43^b	0.37^b	2.28^a	2.02	0.001	0.001	0.002
Urea	0.42^b	0.39^b	0.59^ab	1.07^a	0.21	0.015	0.004	0.123
∑EAA	33.60	25.14	31.32	20.87	4.46	0.247	0.148	0.836
∑NEAA	77.45	71.58	75.84	66.40	7.10	0.711	0.384	0.808
TAA	111.04	96.72	107.16	87.27	11.15	0.473	0.250	0.811

SEM standard error of the mean, EAA essential amino acids, NEAA nonessential amino acids, TAA total amino acids
Dietary treatments were: basal diet + 0, 500, 1000, and 1500 mg/kg GAA, respectively. n = 6
^{a, b}Mean within rows with different letters differ significantly (P < 0.05)
Bold indicates P < 0.05

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ISSN: 2055-5660

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